Ingredient Repository · Ingredient

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Ingredient

Lipase

A natural digestive enzyme that breaks down dietary fats so your body absorbs nutrients easily.

What it is

Lipase is a digestive enzyme that helps your body break down fats and oils from food. Supplemental lipase is made through natural plant fermentation (the natural process bacteria use to break down fibre), allowing it to work in both the stomach and small intestine. This helps digest fats early so you do not feel heavy or greasy after rich meals.

Also known as: Digestive Lipase

Key benefits

  • Breaks down healthy fats into smaller units so your body absorbs them easily.
  • Helps your body absorb fat-soluble vitamins like vitamins A, D, E, and K.
  • Eases fullness, nausea, and heavy discomfort after eating high-fat foods.

Amplified by probiotics

Lipase breaks fats into smaller particles, making them easier for your gut to handle. Friendly probiotic bacteria work alongside lipase by balancing bile acids in your gut. Probiotics also produce nourishing fatty acids that support blood flow in your gut lining, helping you absorb healthy fats without causing gas or bloating in your lower bowel.

Typical dose

500–5,000 FIP/day

The evidence

Evidence: strong

Clinical studies show that taking lipase enzymes improves fat digestion and reduces feeling overly full after meals. Human trials confirm that it helps people with slow fat digestion absorb healthy nutrients comfortably. (Layer et al. 2001, Aliment Pharmacol Ther) (Domínguez-Muñoz 2011, Nat Rev Gastroenterol Hepatol)

  1. Layer P, et al. Human pancreatic exocrine response to nutrients in health and disease. Aliment Pharmacol Ther. 2001;15(1):1-10. PubMed ↗
  2. Domínguez-Muñoz JE. Pancreatic enzyme replacement therapy for pancreatic exocrine insufficiency. Nat Rev Gastroenterol Hepatol. 2011;8(3):162-172. PubMed ↗

Safety & who should check first

Digestive lipase is safe and acts locally in your digestive tract without entering your bloodstream. High amounts may occasionally cause mild stomach cramps or temporary changes in bowel habits. Speak to a doctor or pharmacist first if you have severe digestive conditions or pancreatitis.