Ingredient Repository · Ingredient

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Ingredient

L-Arginine

An essential amino acid that boosts nitric oxide to support blood flow, blood pressure, and energy.

What it is

L-Arginine is a vital amino acid that your body uses to build proteins and produce nitric oxide. Nitric oxide is a key signaling molecule that relaxes and widens blood vessels.

By keeping your blood vessels open, L-Arginine supports healthy blood circulation, heart fitness, and muscle performance during activity.

Also known as: Arginine, L-Arginine Base, L-Arginine HCl

Key benefits

  • Boosts nitric oxide production in blood vessels, so blood flows smoothly throughout your body.
  • Supports healthy blood pressure and arterial flexibility, which means better heart and blood vessel health.
  • Enhances muscle blood flow during exercise, so you feel stronger and recover faster.
  • Supports healthy circulation to reproductive organs, which promotes vitality and intimacy.

Amplified by probiotics

L-Arginine is absorbed through your small intestine. Friendly gut bacteria, such as Lactobacillus and Bifidobacterium, help protect L-Arginine from breaking down too quickly in your digestive tract. Probiotics also produce nourishing compounds that keep your gut lining healthy and reduce gut inflammation. This allows more L-Arginine to enter your bloodstream where it can boost nitric oxide for better circulation.

Typical dose

1,500–6,000 mg/day (divided doses)

The evidence

Evidence: strong

Human studies show that taking L-arginine helps support healthy blood pressure and relaxes blood vessels. Fitness studies also show it helps improve endurance and oxygen delivery during exercise. (Dong JY 2011, Am Heart J) (McRae MP 2016, J Chiropr Med)

  1. Dong JY, et al. Effect of oral l-arginine supplementation on blood pressure: a meta-analysis of randomized, double-blind, placebo-controlled trials. Am Heart J. 2011;162(6):959-965. PubMed ↗
  2. McRae MP. Therapeutic Benefits of l-Arginine: An Umbrella Review of Meta-Analyses. J Chiropr Med. 2016;15(3):184-189. PubMed ↗

Safety & who should check first

L-Arginine is safe for most adults at standard doses. Taking very high amounts at once may cause mild stomach upset. Consult a doctor or pharmacist before use if you have low blood pressure or take blood pressure medications.