Ingredient Repository · Ingredient

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Ingredient

Citrus Bioflavonoids

Natural plant compounds from citrus fruits that strengthen blood vessels and support vitamin C action.

What it is

Citrus bioflavonoids are natural antioxidants found in the peel and pulp of citrus fruits like oranges, lemons, and grapefruits. In supplements, these active compounds include hesperidin, naringin, and rutin. Working together with microencapsulated probiotic cultures, citrus bioflavonoids protect your cells from daily wear and tear on your cells and support healthy blood circulation.

Also known as: Bioflavonoids, Citrus Bioflavonoid Complex

Key benefits

  • Protects delicate capillary walls to support healthy micro-circulation and blood vessel strength.
  • Enhances how your cells absorb and use vitamin C for better antioxidant protection.
  • Neutralises free radicals so your body can reduce daily cell-damaging cell damage.
  • Supports a healthy inflammation in your blood vessels to keep circulation smooth.

Amplified by probiotics

Citrus bioflavonoids are complex plant compounds that can be hard for the upper gut to absorb. Friendly probiotic bacteria like Bifidobacterium and Lactobacillus release natural enzymes in the gut that break down these plant sugars. This converts bioflavonoids into active forms that your body can absorb into the bloodstream. Each probiotic bacterium is shielded by a micro-shield so it arrives safely in your gut to perform this vital task.

Typical dose

100–500 mg/day

The evidence

Evidence: moderate

Human studies show that taking citrus bioflavonoids supports blood vessel function and improves micro-circulation (Rizza 2011, J Clin Endocrinol Metab). Clinical studies also confirm improved artery reactivity and higher antioxidant protection after taking citrus bioflavonoids (Valls 2015, Eur J Nutr).

  1. Rizza S, et al. Citrus polyphenol hesperidin stimulates production of nitric oxide in endothelial cells while improving endothelial function and reducing inflammatory markers in patients with metabolic syndrome. J Clin Endocrinol Metab. 2011;96(5):E782-792. PubMed ↗
  2. Valls RM, et al. Effects of hesperidin consumption on vascular function in subjects with metabolic syndrome: a randomized double-blind crossover trial. Eur J Nutr. 2015;54(7):1217-1227. PubMed ↗

Safety & who should check first

Citrus bioflavonoids are very safe with a long history of dietary use. Mild stomach upset is rare. Speak to a doctor or pharmacist before use if you take prescription medications, especially those processed by the liver.